/ / This is how the third dose of Pfizer will work

This is how the third dose of Pfizer will work

May 27, 2021

Despite consist of two doses, some of the coronavirus vaccine pharmaceutical companies already openly talk about inoculating a third booster dose. This has been expressed by both Pfizer / BioNTech and Moderna, both from the United States. While the first spoke seven to nine months after the first, Moderna set a specific date: in September for the first to receive the first injection.

Now, in addition, we know what this third booster dose will be like in the case of Pfizer. Through a release, report that they have initiated a study to verify the efficacy of a 3rd dose mix of your COVID vaccine with the candidate 20-valent pneumococcal conjugate vaccine (20vPnC).

The objective, they detail, is “to describe the safety when both vaccines are administered together, with a six-month follow-up after vaccination. “Regarding the secondary objectives, they speak of” describing the immune responses produced by each of the vaccines“.

Trial in progress

The study has already started and, as noted by Pfizer, the first registrants have already received the treatment. This trial will consist of 600 adults aged 65 and over, which will come out of those who were already part of the last phase of the clinical trial for the development of its current vaccine against COVID. They must also have received the second dose at least six months ago.

In this study, the volunteers will be separated into three different groups, in order to check the effectiveness of the combination with the candidate vaccine, which is being developed to protect adults against 20 serotypes responsible for most pneumococcal diseases invasive and pneumonia.

Groups for the third dose

  • 20vPnC plus Pfizer’s booster against COVID (third dose, as above)
  • 20vPnC plus placebo
  • Booster Pfizer vaccine plus placebo

One dose with both vaccines

The CEO of the American company, Albert Bourla, shared more details of the research process that tries to find the best solution for this booster dose. “Considering the possible need for a Covid vaccine booster, we are evaluating the co-administration with candidate Prevnar-20. If successful and approved, people could get both vaccines in one dose. “

# COVID19 vaccine booster, we are exploring the co-administration of our Prevnar-20 vaccine candidate with a 3rd dose of our COVID-19 vaccine. If successful and approved, people could get both vaccines in one visit: https://t.co/nsSbx6KdQZ (1/3)

– AlbertBourla (@AlbertBourla) May 24, 2021

“Pfizer’s 20vPnC vaccine candidate includes Conjugated polysaccharide capsules for the 13 serotypes in Prevnar 13 (the 13-valent pneumococcal vaccine) and seven additional serotypes that cause pneumococcal disease that are associated with high mortality rates, antibiotic resistance and / or meningitis. In general, the 20 serotypes included are responsible for the most pneumococcal diseases currently circulating worldwide“, describes the pharmacist about it.


#dose #Pfizer #work



source https://pledgetimes.com/this-is-how-the-third-dose-of-pfizer-will-work/

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